中文版
Natural Bulk Compounds
Cyclopamine
Catalog No. :
C10560
Product Name :
Cyclopamine
CAS No. :
4449-51-8
Synonyms :
11-Deoxojervine
Chemical Name :
Molecular Formula :
C27H41NO2
Molecular Weight :
411.62
Molecular Structure :
Appearance :
White crystalline solid
Specification :
In-House Standard
Application :
Registration :
Storage Condition :

Biological ActivityInhibitor of hedgehog (Hh) signaling, likely via direct inhibition of Smoothened, the accessory protein to the putative Hh receptor Patched. Anticancer and teratogenic in vivo. Depletes stem-like cancer cells in glioblastoma and blocks tumor engraftment. Can also be used to induce differentiation of human embryonic stem cells (hESCs) into hormone-expressing endocrine cells. 

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->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.

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